Tuesday, January 18, 2022
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FDA authorizes second COVID-19 antiviral capsule


The Food and Drug Administration licensed a second at-home antiviral capsule to deal with COVID-19 on Thursday. The clearance for the drug, known as molnupiravir, got here a day after the company signed off on Pfizer’s COVID-19 antiviral, known as Paxlovid. Both medication scale back the danger of hospitalization and dying in individuals identified with COVID-19 and prone to having a extreme case of the illness.

Molnupiravir, made by pharmaceutical firm Merck, is allowed for individuals 18 years of age and older who’re at a excessive threat of getting significantly ailing in the event that they contract the coronavirus. It’s the next age cutoff than Paxlovid, which is cleared for individuals 12 and up, as a result of molnupiravir would possibly have an effect on bone and cartilage progress, the FDA stated in an announcement.

Like Paxlovid, sufferers have to begin taking Merck’s drug inside a couple of days of growing signs to ensure that it to be the best. That may be troublesome within the United States, the place testing to verify somebody has COVID-19 is usually sluggish and restricted — significantly throughout surges in case numbers when therapies are most wanted.

Molnupiravir initially appeared to chop the danger of hospitalization and dying by about half in a scientific trial. Additional analysis, although, discovered that it was solely round 30 % efficient. That’s far much less efficient than Paxlovid, which decreased hospitalizations and deaths for high-risk teams by 89 % in a scientific trial.

Despite its decrease efficacy, the US could also be reliant on molnupiravir within the close to future — the Biden administration expects to have 3 million programs of the Merck drug obtainable by the top of January however solely 265,000 programs of Paxlovid. The federal authorities began allocating programs of Paxlovid to states after its authorization yesterday.

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